Major Advances in Triple-Negative Breast Cancer Treatment Happening in Clinical Trials

Len Lichtenfeld MD MACP

DR Len Lichtenfeld MD
Former Deputy Chief Medical Officer for American Cancer Society 

“Many still think triple-negative breast cancer is the disease it was as recently as 5 years ago. News bulletin: it is not. 

It is detectable, it is treatable, and for some survivable in a way we wouldn’t have dreamed of even recently.

The number of new drugs either approved for treatment or in the pipeline of clinical trials is mind boggling

We need to ditch the stigma, treat the disease, and make certain everyone with triple-negative breast cancer has access to the best possible care.”

TNBC Breakthrough Immunotherapy-Chemo Combination Trial Results Published in The Lancet September 2020

69%

Absence of  invasive cancer shown in 69% of patients in the immunotherapy-chemo combination group

20%

20% more patients in the immunotherapy-chemotherapy group showed absence of invasive cancer

“Patients with cancer treated in clinical trials lived longer”

Penn State Cancer Institute - 2020 study of 12 million patients

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Possible Advanced Treatments Received in Clinical Trials

Immunotherapy

Triggers the body’s immune system to fight the cancer

Targeted Therapy

Directed against a specific protein or molecule in the cancer

PD-L1 Inhibitor

Blocks activity of proteins that keep body from fighting cancer

Immuno Combinations

Chemotherapy or other other treatment taken in together with immunotherapy

Chemo

Chemicals that kill fast-growing cells in the body

Quality of Life

Improving of symptoms, well-being and quality of life

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