Major Advances in NSCLC Cancer Treatment Happening in Clinical Trials

Len Lichtenfeld MD MACP

Len Lichtenfeld MD MACP
Former Deputy Chief Medical Officer for American Cancer Society 

“Many still think lung cancer is the disease it was as recently as 5 years ago. News bulletin: it is not. 

It is detectable, it is treatable, and for some survivable in a way we wouldn’t have dreamed of even recently.

The number of new drugs either approved for treatment or in the pipeline of clinical trials is mind boggling

We need to ditch the stigma, treat the disease, and make certain everyone with lung cancer has access to the best possible care.”

NSCLC Breakthrough Trial Results Published October 2020 in the New England Journal of Medicine

90%

Stage IB to IIIC non-small cell lung cancer had a close to 90% survival at two years while 52% in placebo group were alive.

80%

Overall, treatment resulted in an 80% reduced chance of dying for patients who received it as part of the clinical trial.

“Patients with cancer treated in clinical trials lived longer”

Penn State Cancer Institute - 2020 study of 12 million patients

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Possible Advanced Treatments Received in Clinical Trials

Immunotherapy

Triggers the body’s immune system to fight the cancer

Targeted Therapy

Directed against a specific protein or molecule in the cancer

PD-L1 Inhibitor

Blocks activity of proteins that keep body from fighting cancer

Chemotherapy

Chemicals that kill fast-growing cells in the body

Radiation

High-energy particles that destroy cancer cells by breaking their DNA

Quality of Life

Improving of symptoms, well-being and quality of life

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