Clinical trials are a safe way to gain access to patient care alternatives that are being evaluated by top companies and health care organizations – they offer novel and potentially life-saving treatments to participants before those treatments become available on the open market. Understanding clinical trials is key to participating and possibly benefitting from these groundbreaking treatments…
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Cancer Trials Suspended Due to COVID-19
|Clinical Trial Title||Trial Sponsor||NCT ID|
|Collecting and Storing Tissue Samples From Women With or Without Breast Cancer||National Cancer Institute (NCI)||NCT00899301|
|Prospective Construction and Validation of a Prognostic Score to Identify Among Patients With Metastatic Breast Cancer Those Who Benefit From a Third Line Chemotherapy in Terms of Overall Survival||Institut Claudius Regaud||NCT01574170|
|Topical or Ablative Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Squamous Intraepithelial Lesions||AIDS Malignancy Consortium||NCT02135419|
|Vaccine Therapy and Pembrolizumab in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer||Madison Vaccines Inc||NCT02499835|
|Monitoring Neoadjuvant Chemotherapy Response in Breast Cancer Patients Using Diffuse Optical Spectroscopic Imaging||Boston Medical Center||NCT02510456|
|Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies||Fred Hutchinson Cancer Research Center||NCT02706392|
|FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging||National Cancer Institute (NCI)||NCT02773238|
|Cost Utility of Radical Surgery in Ovarian Cancer||Institut Claudius Regaud||NCT02854215|
|Evaluation of an Organized Consultation Return Home of Patients With a Cancer (CREDO)||Institut Claudius Regaud||NCT02857400|
|Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery||National Cancer Institute (NCI)||NCT02881554|
|Interest of elastoFRM With Force Measure by MRI on Patients With Hepatocellular Cancer||Assistance Publique - Hôpitaux de Paris||NCT02929082|
|Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs||Taiho Pharmaceutical Co. Ltd.||NCT02943733|
|FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer||University of Wisconsin Madison||NCT03212170|
|Phase I/II Trial of Regorafenib Hydroxychloroquine and Entinostat in Metastatic Colorectal Cancer||Abramson Cancer Center of the University of Pennsylvania||NCT03215264|
|PSMA-based 18F-DCFPyL PET/CT and PET/MRI Pilot Studies in Prostate Cancer||University of Wisconsin Madison||NCT03232164|
|Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer||Merck Sharp & Dohme Corp.||NCT03260504|
|Patient Navigation in Cancer Survivorship at a Safety Net Institution||Boston Medical Center||NCT03271099|
|PSMA PET and MRI in Gynecological Cancers||University of Wisconsin Madison||NCT03302156|
|PET-MRI Assessment of Early Tumor Response to Predict Outcomes of HPV-Positive Oropharynx Cancer Patients||National Cancer Institute (NCI)||NCT03342378|
|Pilot Trial of Chemohormonal Therapy Followed by Prostatectomy in High Risk Prostate Cancer||National Cancer Institute (NCI)||NCT03358563|
|A Study to Test Different Doses of BI 836880 Combined With BI 754091 in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours||Boehringer Ingelheim||NCT03468426|
|The Prevent Anal Cancer Self-Swab Study||Baylor College of Medicine||NCT03489707|
|Avelumab With Chemoradiation for Stage II/III Resectable Esophageal and Gastroesophageal Cancer||University of Wisconsin Madison||NCT03490292|
|Outcomes of Focal Therapies for Prostate Cancer||Weill Medical College of Cornell University||NCT03492424|
|Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer||National Cancer Institute (NCI)||NCT03505671|
|Monitoring of Immunological Mechanisms and Biomarkers Underlying Efficacy and Toxicity of Cancer Immunotherapy||Institut Claudius Regaud||NCT03514368|
|Defining the Molecular Profile of Breast Cancer in Uganda and Its Clinical Implications||Fred Hutchinson Cancer Research Center||NCT03518242|
|Olaparib Before Surgery in Treating Participants With Localized Prostate Cancer||AstraZeneca||NCT03570476|
|pTVG-HP and Nivolumab in Patients With Non-Metastatic PSA-Recurrent Prostate Cancer||AIQ Solutions||NCT03600350|
|The Use of FES-PET Imaging as a Tool to Detect a Possible Reversion of Estrogen Receptor (ER)-α Status in Patients With Metastatic Breast Cancer HER2 + and ERα Neg Treated With Trastuzumab + Pertuzumab + Taxane.||Institut Claudius Regaud||NCT03619044|
|A Prospective Randomized Trial Comparing Office-based MR-guided Prostate Biopsy Approaches||Weill Medical College of Cornell University||NCT03632655|
|Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS||National Cancer Institute (NCI)||NCT03703492|
|Evaluation of the Feasibility and Clinical Relevance of Liquid Biopsy in Patients With Suspicious Metastatic Lung Cancer||Centre Leon Berard||NCT03721120|
|Occupational Therapist-Led Work Intervention in Facilitating Work Maintenance or Re-entry to the Workforce in Patients With Stage I to III Breast Cancer Undergoing Chemotherapy||National Cancer Institute (NCI)||NCT03723863|
|Study of the Efficacy of Lenvatinib Combined With Denosumab in the Treatment of Patients With Predominant Bone Metastatic Radioiodine Refractory Differentiated Thyroid Carcinomas||Centre Leon Berard||NCT03732495|
|ONC201 With and Without Methionine-Restricted Diet in Patients With Metastatic Triple Negative Breast Cancer||The V Foundation for Cancer Research||NCT03733119|
|Cetuximab in Head and Neck Cancer Patients||American Cancer Society Inc.||NCT03769311|
|Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases||National Cancer Institute (NCI)||NCT03796273|
|Medical Data Collection in the Formation of Precision Oncology Registry||National Cancer Institute (NCI)||NCT03874065|
|Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)||Immunomedics Inc.||NCT03901339|
|Modified Immune Cells (Autologous CAR T Cells) in Treating Patients With Advanced Recurrent Platinum Resistant Ovarian Fallopian Tube or Primary Peritoneal Cancer||Fred Hutchinson Cancer Research Center||NCT03907527|
|Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients||University of Wisconsin Madison||NCT03933813|
|Platino-resistance in Ovarian Cancer||Institut Claudius Regaud||NCT03954171|
|Evaluation of PET-CT Scanner Performances to Detect Infra-centimetric Lesions in Patients With Cancer||Institut Claudius Regaud||NCT03956459|
|Deciphering Mechanisms Underlying Cancer Immunogenicity||Institut Claudius Regaud||NCT03958240|
|Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy||National Cancer Institute (NCI)||NCT03958747|
|A Study of Sacituzumab Govitecan in Metastatic Solid Tumors (TROPICS-03)||Immunomedics Inc.||NCT03964727|
|A Prospective Study to Collect Images in Patients Treated With Iodine-131 as Part of a European Research Project in Radiation Protection.||Institut Claudius Regaud||NCT03986437|
|AREG EREG and EGFR: Response to Anti-EGFR Agents in Colorectal Cancer||Newcastle University||NCT03986541|
|Paclitaxel Therapeutic Drug Monitoring in Cancer Patients||National Cancer Institute (NCI)||NCT03987555|
|Characterize Tumor Hypoxia by Magnetic Resonance Imaging||National Cancer Institute (NCI)||NCT03987568|
|Metabolic and Microbial Profiling of Lung Cancer||National Cancer Institute (NCI)||NCT03998189|
|Exhaled Breath Analysis to Predict Risk of Symptomatic Pneumonitis||National Cancer Institute (NCI)||NCT04040244|
|The Prevent Anal Cancer Palpation Study||Baylor College of Medicine||NCT04090060|
|pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant Metastatic Prostate Cancer||Madison Vaccines Inc||NCT04090528|
|Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy||KeraNetics LLC||NCT04173247|
|FES Imaging to Optimize Tamoxifen for Metastatic Breast Cancer||University of Wisconsin Madison||NCT04174352|
|Lifestyle Program (Scalable Nutrition and Physical Activity) for the Improvement of Nutrition and Physical Activity in Stage 0-III Breast Cancer Survivors||Breast Cancer Research Foundation||NCT04200482|
|E-monitoring of Patients Under Adjuvant Hormonotherapy for Breast Cancer.||Institut Claudius Regaud||NCT04228432|
|Prevalence and Impact on QoL From Ototoxicity in Cancer Survivors||International Stem Cell Forum||NCT04270916|
|LCCC1931:Post-treatment Intervention in Women With Breast Cancer (70y/o+)||UNC Lineberger Comprehensive Cancer Center||NCT04292847|
From the Community
Over the recent past, medical advancements, even in terms of research and analysis, have grown sporadically. These advancements have birthed some practical practices, one of them being clinical trials for breast cancer. You may be wondering what these trials mean and what they encompass. Even with a slight understanding, I can assure you that many are the benefits that come along with this practice…
In The News
Patients, drug makers grapple with how to continue cancer trials during the coronavirus STAT - April 29th
The coronavirus pandemic has thrown a wrench into plans for hundreds of clinical trials seeking therapies for diseases beyond Covid-19. But some investigators and sponsors are trying to push ahead, tailoring ways to keep patients enrolled while keeping them safe and to ensure the trial can still produce rigorous evidence of whether or not a drug works.
How to Think About Your Cancer Care in the Time of COVID-19 TIME - April 28th
Getting the news that you have cancer is overwhelming and frightening. The COVID-19 crisis adds another layer of anxiety. But know this: you can protect yourself from COVID-19 without compromising your cancer treatment. Don’t panic. In the vast majority of cases, a diagnosis of cancer is not an emergency even though it feels like one. There is time to learn about your options and sort out what is right for you.
The Pandemic’s Hidden Victims: Sick or Dying, but Not From the Virus New York Times - April 20th
As the coronavirus overwhelms the health care system, people with other illnesses struggle to find treatment.
Twin Cities nonprofit steps up to help cancer patients during COVID-19 pandemic Eyewitness News - April 15th
The Angel Foundation, based in Mendota Heights, told 5 EYEWITNESS News they had received many calls from cancer patients who are struggling financially due to lack of work and medical bills.
Oncologists, patients weigh treatment and coronavirus risk. ‘Cancer is a disease that does not wait.’ Chicago Tribune - April 10th
As the coronavirus pandemic intensified, so did Catherine Payne’s strategies for avoiding infection while undergoing chemotherapy. The 33-year-old West Town woman was diagnosed with stage 3 breast cancer in November and began treatment soon after, suppressing her immune system.
Woman's cancer treatments put on hold due to Ohio Department of Health's order ABC Cincinnati - April 8th
Coronavirus stopped Carol Ann Horn’s cancer treatments before they could even get started. Her surgery was canceled because of state orders that aim to stop the spread of COVID-19 by postponing certain surgeries.
Cancer Patients Face Treatment Delays and Uncertainty as Coronavirus Overwhelms Hospitals Scientific American - April 8th
The federal government has encouraged health centers to delay nonessential surgeries while weighing the severity of patients’ conditions and the availability of personal protective equipment, beds and staffing at hospitals.
Cancer Patients Are at Higher Risk From Coronavirus Infection Wall Street Journal - April 8th
Treatments like chemotherapy can weaken immune systems, making cancer patients more likely to contract Covid-19
How to Live in the Face of Fear: Lessons From a Cancer Survivor New York Times - April 7th
As the coronavirus pandemic spreads, the normal touchstones of everyday life have vanished without so much as a warning. In their place are terrifying thoughts about the future, about loss and about mortality.
As Coronavirus Strains Hospitals, Cancer Patients Face Treatment Delays, Uncertainty NPR - April 2nd
Two days before Christine Rayburn was scheduled to have a cancerous tumor removed, the hospital cancelled the surgery, part of a wave of cancellations of "elective" surgeries during the coronavirus pandemic. But Rayburn's surgeon fought back, and got the surgery back on the schedule 10 days later.
Sacramento cancer patient fears medical professionals prioritize 'healthier' people as COVID-19 cases surge ABC7News - April 2nd
Last weekend, Valerie received a call from an oncology supervisor at Sutter General Hospital, who advised her to stay away from the emergency room during a COVID-19 surge.
Cancer in the coronavirus crisis: My weekly diary The Guardian - March 30th
Heather Chaney, 49, is a stay-at-home mom from Bellevue, Washington. She was diagnosed with cervical cancer in mid-February 2020, just weeks before the coronavirus outbreak overwhelmed the state.
Coronavirus is forcing N.J. hospitals to postpone cancer surgeries. Here’s one couple’s agonizing experience. NJ.com – March 30th
For nearly 40 years, Patricia Duffy has sat at her husband’s side. The two are inseparable, having built a life together, having raised three children together..
Cancer patients missing out on 'vital' treatment due to COVID-19 Sky News – March 29th
A leading oncologist has said “the highest priority” sufferers may “not be able to get treatment and this is a tragedy”.
With Hospitals Strained, Some Cancer Patients Face Delays In Treatment NPR – March 29th
Cancer patients are facing delays in treatment as hospitals and doctors focus their efforts on fighting the coronavirus.
Coronavirus concerns lead to postponement of cancer treatments 10 News San Diego – March 27th
A local patient with an advanced cancer says she’s fearful after being told her upcoming treatment has been postponed.
Some cancer patients face delayed surgeries and scaled-back treatments as the coronavirus advances Washington Post – March 24th
Patients and doctors struggle to confront the twin threats of cancer and covid-19. While many treatments won’t be changed, some surgeries can be safely postponed, say doctors who are trying to reduce patients’ time in the hospital.
Which cancer patients should be continuing chemotherapy during the coronavirus? | Ranjana Srivastava The Guardian – March 24th
Here are some questions that all chemotherapy patients should ask their oncologist