What is Brain Cancer Treatment?

Matt Ewend, MD., UNC Chairman of Neurosurgery Explains

Understanding Brain Cancer Treatment

The first step in the treatment of a patient with a brain tumor is to get a diagnosis and to frequently remove as much of the tumor as can safely be removed.  At this point you may find that your team of doctors and healthcare professionals broadens and you may meet a medical oncologist or neuroncologist which is a doctor who specializes in giving chemotherapy and medicine to treat tumors. You may also meet a radiation oncologist. That’s not a radiologist. A radiologist looks at x-rays like the MRIs that you probably had. The radiation oncologist treats tumors with radiation and often at this point the neurosurgeon, someone like me, will take a step back on your team and be a supporting member of the team and the medical oncologist partnered with the radiation oncologist will take the lead in treatment. 

Some patients with very low-grade tumors like grade 1 tumors and some grade 2 tumors who are young and have had a very good removal might just elect for observation at this point, meaning we would do a series of MRI scans over months and years to follow for any sign of the tumor coming back. It’s very important for anybody diagnosed with a brain cancer to have a long-term follow-up plan and it would be very unusual after surgery for me to tell a patient that they didn’t need to come back anymore, even if they were only coming back for scans. So if you hear that you don’t need any more MRIs or anything else done it would be very good to ask, and make sure that that’s clearly the point, because most patients will at least get follow-up imaging.  

Many patients with grade two tumors and almost all patients with grade 3 and grade 4 tumors even after the best surgical resection will hear recommendations from their treatment team to consider chemotherapy or radiation therapy. Sometimes the two are given together. It’s very common to set out a treatment plan that would go on for a number of months and it might be that the patient would get radiation as the first step. Maybe with a low dose of chemotherapy given at the same time, then take a brief pause and then move on to getting regular chemotherapy for a defined period of time. Or at that point the period of time may not be known. So you should often expect to hear at this visit about a treatment plan that would involve both radiation and chemotherapy. Obviously this has to be individualized for each patient’s case.

Own Your Brain Cancer Treatment

What is TrialJectory?

Personalized brain cancer treatment options. 100% Free.

“This is important for every cancer patient to know: You have to advocate for yourself. Don’t take no for an answer too easily” 

Dr. Bernard Chinnasami,
Medical Direct & Senior Oncologist


“Anyone who has to hear the words ‘you have cancer’ should see what’s a match at TrialJectory right away.”

Hailey Werge,
Breast Cancer patient

“Patients with cancer treated in clinical trials lived longer”

Penn State Cancer Institute – 2020 study of 12 million patients

“Cancer patients enrolled in clinical trials receive the best management of care” 

 -NCCN 2019 Guidelines

How TrialJectory Empowers Brain Cancer Patients

Know YOUR Brain Cancer Treatment Options

Brain cancer research is evolving so rapidly it’s become impossible for oncologists to be aware of all options. TrialJectory creates a personalized list of brain cancer clinical trials that matches your exact diagnosis.

AI Decision Assistance

Our artificial intelligence technology curates massive volumes of bladder cancer research data and instantly presents it in easy to understand language. You can share the results with your oncologist and together make the right decisions about your brain cancer treatment. 

You’re Not Alone

See the brain cancer treatments of other patients like you with our Treatment Finder. You’ll see how many patients received different treatments and the same treatments, the outcome, and which clinical trials they were matched to.

No Big Budget Bias

Explore options without the influence of drug company and hospital advertising budgets. The company that spends the most on marketing their brain cancer drugs should not determine your cancer treatment. 

"TrialJectory researched all cancer treatment options. They've been amazing"​

Brenda Shawley

Colon Cancer Patient


Ready to Own Your Brain Cancer Journey?

  1. Complete the brain cancer questionnaire
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  3. Compare patients’ treatment like yours
  4. Learn about the treatment or trial that’s right for you
  5. Get the guidance you need

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